Etizolam VS Xanax

Etizolam VS Xanax: Which is Stronger and More Effective

Are you struggling with insomnia, anxiety, or depression? You’re not alone. Many people turn to medications like Etizolam and Xanax to find relief. But which one is stronger and more effective? In this blog, we’ll delve into the key differences between Etizolam and Xanax to help you make an informed decision. Whether you’re searching for the right treatment or simply curious about these medications, this comprehensive comparison will provide you with valuable insights. Let’s explore the potency and effectiveness of Etizolam vs. Xanax to help you find the best solution for your needs.

A Quick Comparison of Etizolam Vs. Xanax

PropertyXanax (Alprazolam)Etizolam
StrengthPotent, strong sedative, higher dependence riskSimilar potency, lower addiction potential
Duration11-13 hours half-life, peak effect within 6 hours6-8 hours, shorter half-life of 8 hours
EffectsAnxiolytic, sedative, hypnotic, euphoria, memory loss, coordination impairmentAnxiolytic, hypnotic, anticonvulsant, muscle relaxant, less likely to cause tolerance
Standard Dose0.25-3 mg for therapeutic use, >4 mg for recreational0.25-3 mg for therapeutic use, >4 mg recreational
Abuse PotentialHighModerate

1. Xanax (Alprazolam) Properties

Alprazolam, also known by the trade name Xanax, is one of the most commonly prescribed benzodiazepines. It is primarily used as an anti-anxiety medication for conditions such as general anxiety disorder and panic disorder. Additionally, it has been prescribed for chemotherapy-induced nausea. Alprazolam comes in pill form and has an oral bioavailability of eighty to ninety percent. It’s worth noting that alprazolam (Xanax) is also a popular recreational drug in popular culture.

  • Etizolam Tablets 1mg
  • Etizolam Tablets 2mg

Strength

Xanax (alprazolam) is a potent and commonly prescribed benzodiazepine available in the market today. It is approximately equal in potency to etizolam but has several different effects and traits that set the two apart. Xanax has a stronger sedative effect than etizolam, is more likely to cause memory loss, and has a higher dependence liability.

Duration

Xanax (Alprazolam) is a short-acting benzodiazepine with a half-life of eleven to thirteen hours. The maximum effects of Xanax are experienced within six hours.

Effects

Xanax (Alprazolam) is a highly effective medication for treating anxiety, as well as a sedative and hypnotic. It can also act as a potent intoxicant. Common effects of Xanax use include euphoria, memory loss, coordination and motor skill impairment, drowsiness, relaxation, and reduced inhibitions. Intoxication from Xanax closely resembles alcohol intoxication. Compared to etizolam, Xanax has a higher potential for abuse.

Standard Dose

Alprazolam doses range from 0.25 milligrams per pill to four-milligram “bars.” Doses between one and four milligrams are prescribed to manage general anxiety disorder and panic disorder. Alprazolam doses exceeding four milligrams are considered recreational and are used for non-medical purposes.

2. Etizolam Properties

Etizolam is not a true benzodiazepine like alprazolam, but rather a thienodiazepine derivative benzodiazepine analog. It is sold under various brand names, such as Etilaam, Etizest, Pasaden, Depas, and Etizola. Etizolam can be taken orally, sublingually, or rectally, while alprazolam is only available as an oral pill. Etizolam has a 93% oral bioavailability, compared to alprazolam, which only has an 80-90% oral bioavailability. This makes etizolam a more effective drug than alprazolam overall.

Strength

Etizolam is approximately as potent as Xanax (alprazolam), although it is not usually available in doses higher than two milligrams per pill. Alprazolam tends to have a more powerful sedative effect than etizolam, making it a better option for treating insomnia. Additionally, alprazolam has a higher likelihood of causing benzodiazepine addiction and withdrawal symptoms compared to etizolam.

Duration

Etizolam usually has a slightly longer action term than Xanax at six to eight hours rather than Xanax’s six-hour maximum. Etizolam also has a much shorter half-life than Xanax at just over eight hours.

Effects

Etizolam has anti-anxiety, hypnotic, anticonvulsant, and skeletal muscle relaxant properties in addition to its anti-anxiety effects, while Xanax only has sedative-hypnotic and anxiolytic properties. Etizolam is less likely to cause tolerance and dependence than Xanax due to its unique reverse tolerance effect. This effect causes it to become even more effective over time rather than less effective like most benzodiazepines and other drugs. Etizolam is considered to have only moderate potential for abuse compared to Xanax.

Standard Dose

Etizolam is about as potent as Xanax and is available in similar dose ranges: 0.25-milligram, 0.5-milligram, 1-milligram, and 2-milligram pills. Unlike Xanax, etizolam is not produced in doses as high as four milligrams. The recommended maximum therapeutic dose for etizolam is three milligrams per day. Recreational use typically begins at four milligrams of etizolam.

3. Diclazepam vs. Etizolam

Diclazepam

Diclazepam is a relatively recently rediscovered experimental designer benzodiazepine synthesized in the 1960s but never actually marketed. Diclazepam is a sedative-hypnotic and a more powerful analog of diazepam, better known by the trade name Valium. Etizolam and diclazepam are about equally effective.

Strength

Diclazepam and etizolam have similar potency, with diclazepam being ten times stronger than its parent drug, diazepam. One milligram of diclazepam is equivalent to one milligram of etizolam.

Duration

Diclazepam is taken either orally or sublingually. It takes between ten and forty-five minutes for diclazepam to take effect, and it is a relatively long-acting benzodiazepine with a duration of ten to twelve hours.

Effects

Diclazepam is a potent drug used for anxiety and to induce sleep. It also has anticonvulsant and muscle relaxant properties. Within the body, diclazepam breaks down into other medicines such as lorazepam, delorazepam, and lormetazepam. Its effects include drowsiness, disinhibition, loss of motor coordination, short-term memory loss, and euphoria.

Standard Dose

Diclazepam starts working at doses as low as a half milligram. Four milligrams is a relatively heavy dose of diazepam and is in the recreational range.

Etizolam

Etizolam is similar in strength to diclazepam but shorter-acting and less sedating. It is the only drug known to possess the reverse tolerance phenomenon. Etizolam has a history of approved medical use, while diclazepam is still a designer drug lacking information about long-term effects on human beings.

Strength

Etizolam is roughly the same strength as diclazepam. One milligram of either substance is equal to ten milligrams of diazepam.

Duration

Etizolam has a relatively brief duration of action compared to diclazepam. Its effects peak between thirty minutes and two hours after onset and last between six and eight hours. In contrast, diclazepam lasts from ten to twelve hours.

Effects

Etizolam has many of the same therapeutic results as diclazepam, though diclazepam is no longer acting. Both drugs cause short-term memory loss, poor coordination, and sedation, however, etizolam causes less drowsiness and memory loss than diclazepam. Etizolam is preferred for recreational use due to its fast onset, pleasant body buzz, short half-life, and brief duration of effects.

Standard Dose

A mild dose of one milligram of etizolam is just as effective as a milligram of diclazepam. Four milligrams would constitute a heavy dose of either drug.

4. Metizolam vs. Etizolam

  • Etizolam Tablets 1mg
  • Etizolam Tablets 2mg

Metizolam

Metizolam, also known as desmethyletizolam, is a thienotriazolodiazepine and a less potent, demethylated analog of etizolam. It is approximately half the strength of standard etizolam, which is the more effective of the two drugs.

Strength

Metizolam is approximately half the potency of etizolam.

Duration

Metizolam has a reasonably moderate duration of five to eight hours and a sixty percent longer half-life than etizolam does.

Effects

Metizolam is an anxiolytic, sedative-hypnotic, anticonvulsant, and skeletal muscle relaxant. Its effects include calmness, peace, relaxation, euphoria, and a subtle yet pleasant body buzz. Higher doses may lead to loss of inhibition, drowsiness, and lack of coordination.

Dose

While no standardized dosage is available for metizolam, a typical starting dose is one milligram, while a heavy dose constitutes six or more milligrams.

Etizolam

Etizolam is metizolam’s parent drug, and as such, the two share many similar traits and effects. Etizolam is the methylated version of metizolam.

Strength

Etizolam is approximately twice as potent as metizolam, with 1 milligram of etizolam being equivalent in strength to 2 milligrams of metizolam.

Duration

Etizolam lasts between six and eight hours, roughly the same length as metizolam.

Effects

Etizolam and metizolam have nearly identical effects. Both drugs are effective as anxiolytics, sedatives, anticonvulsants, skeletal muscle relaxants, and intoxicants. The only difference in their effects is etizolam’s higher potency and metizolam’s slightly longer duration of action.

Dose

The standard dose of etizolam for a general anxiety disorder or panic disorder is one milligram per day. The dosage for insomnia is one to two milligrams before bedtime. Three milligrams is a considerably heavy dose, and four milligrams or above constitutes a recreational dose. It takes two milligrams of metizolam to equal a single milligram of etizolam, so it would take twice as much metizolam to achieve the same effects.

5. Flubromazolam vs. Etizolam

Flubromazolam

Flubromazolam is a recently developed, highly potent designer benzodiazepine derivative that is active in very small doses. It is currently only available on the grey market as a designer drug. Due to its inconsistency and extreme strength, etizolam is considered a safer option compared to flubromazolam.

Strength

Flubromazolam is an extremely potent new benzodiazepine derivative. It is active in microgram-sized doses starting at one hundred micrograms.

Duration

Flubromazolam starts to take effect thirty minutes to an hour after the dose is consumed. Along with its high potency, flubromazolam has an unusually long duration of effect: eighteen hours.

Effects

Flubromazolam has a similar effect profile to most other benzodiazepines. It can cause disinhibition, euphoria, lack of coordination, loss of balance, memory loss, drowsiness, and respiratory depression. It is reported to be one of the most euphoric and sedating benzodiazepines. Flubromazolam is less effective for treating anxiety than etizolam, but it is more effective for treating insomnia.

Dose

The typical dose of flubromazolam ranges from 1 to 200 micrograms for a mild effect and 300 to 400 micrograms for a heavy effect. Etizolam is well-known for its sedative properties. Flubromazolam is currently only available on blotter paper as the dosage is too small to be made into pills.

Etizolam

It is much less potent than flubromazolam, but it is safer and much easier to measure and control. It has undergone clinical trials and has been the solution for anxiety medication in Japan and India for decades. Flubromazolam is much stronger than etizolam, but it is a relatively new designer benzodiazepine derivative that hasn’t undergone much human testing yet and may be dangerous to take long-term.

Strength

Flubromazolam is much stronger than etizolam. Etizolam is measured in milligrams, while flubromazolam is so potent it needs to be measured in micrograms. One milligram of etizolam is roughly equal in strength to one hundred and fifty micrograms of flubromazolam.

Duration

The etizolam has a much shorter duration than flubromazolam. The etizolam lasts between six and eight hours while flubromazolam lasts eighteen hours.

Effects

Etizolam and flubromazolam share many effects, including disinhibition, sedation, drowsiness, poor motor coordination, euphoria, relaxation, and difficulty staying awake.

Standard Dose

This drug is much easier to take than flubromazolam. Since flubromazolam is so potent, one should dissolve it in liquid, and then the liquid needs to be dropped on blotter paper-like LSD. This can be imprecise, making flubromazolam less consistent than etizolam and hence possibly more dangerous to take.

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