Etizolam Dosage

Etizolam Dosage and Risks Involved in Overdose

Whether you are taking etizolam for medicinal or recreational purposes, it is essential to know the correct dosage needed to achieve the desired effect. The following is a detailed guide to help you make an informed decision on what etizolam dose works best for you. Whether you are treating panic attacks, symptoms of insomnia, anxiety, and muscle aches, or if you’re looking for a pleasant recreational high without worrying about the dangers of taking impure street drugs.

  • Etizolam Tablets 1mg
  • Etizolam Tablets 2mg

Properties and Uses of Etizolam

Etizolam is a thienotriazolodiazepine, a thieno diazepine derivative used to treat insomnia, epilepsy, convulsions, panic attacks, and anxiety disorders. Unlike “classic” benzodiazepines such as diazepam, etizolam has a different molecular structure in which the benzene ring is replaced by a thiophene ring and then fused with a triazole ring. This means that while it has many of the same effects as benzodiazepines, etizolam is not, in fact, a true benzodiazepine itself but rather a chemical analog.

Etizolam has narcotic, sedative, and anxiolytic effects similar to classic first generation benzodiazepine drugs like diazepam and clonazepam and triazolobenzodiazepine such as alprazolam. While it was never marketed for use in the United States. Etizolam has been used in the Indian, Japanese, and German medical industry consistently for several decades as a powerful and effective sedative, hypnotic, anticonvulsant, skeletal muscle relaxant, and anti-anxiety drug. Well, known pharmaceutical brands of etizolam include Etizola, Depas, Etilaam, Sedekopan, Etizex, and Etizest.

Etizolam High; Is it Real?

Etizolam has many pleasurable effects that make it a highly desirable recreational substance such as euphoria, lowered inhibitions, reduced anxiety, and skeletal muscle relaxation. It can be taken orally, sublingually, rectally, and intravenously when dissolved and diluted in a solution of water and propylene glycol. Etizolam is most commonly available in pill form, however. Etizolam has a ninety-three percent oral bioavailability, meaning that your body will absorb ninety-three percent of the dose if swallowed making it impractical and unnecessary to snort or inject it to feel the drug’s full effects. The oral route is the least invasive and most effective way of maximizing the impact of etizolam for either medicinal or recreational use.

Etizolam starts to take effect between 30-60 minutes after oral use. The high peaks occur between thirty minutes and two hours after onset and last for an average of six hours. Etizolam creates feelings of calm, confidence, euphoria, and relaxation. It causes a pleasant body high comparable to that of Xanax while making the user feel more relaxed and friendly. Etizolam wipes the mind clear of stress and anxiety allowing you to focus on the present worry-free. Etizolam can be used as a party drug or to wind down after a stressful day. It is also used to relieve uncomfortable stimulant comedowns and hangovers effectively and to relieve withdrawal symptoms of alcohol and opioids.

Etizolam Dose:

The standard etizolam dosage depends on what sort of effect you want to achieve. The most common uses of etizolam are as an anti-anxiety medication, and insomnia treatment, or as a recreational drug. Etizolam is typically manufactured in 0.25mg, 0.5mg 1mg and 2mg tablets for prescription use. The recommended maximum medicinal dose of etizolam is three milligrams a day.

Dose Adjustment:

Other factors may affect the potency of etizolam and may necessitate dose adjustment. Generally, more significant people will require larger doses, while smaller individuals might require less to achieve the same effect. Everyone metabolizes substances differently; however, so some experimentation may be necessary until you find the dose that suits your purpose the best. Some of these factors include genetics, weight, age, other medications, an existing tolerance to benzodiazepines or alcohol use.


Etizolam is a potent anxiolytic drug. It works by binding to the brain’s GABA receptors which regulate our anxiety and inhibitions. According to some studies, etizolam is six times more effective than Valium in treating anxiety disorders. For addressing the symptoms of social anxiety disorder, panic disorder, and general anxiety disorder, the recommended dose is 1mg a day. Everyone reacts differently to medications, including etizolam. If you find etizolam to be either too sedating or ineffective, you can adjust your dosage up or down as needed until you find the dose that is right for you.


Etizolam is also a sedative-hypnotic and can function as an effective sleeping pill. For dealing with insomnia, the recommended dosage for insomnia is one to two milligrams a day at night about an hour before bedtime. Due to its unique reverse tolerance effect, etizolam retains its effectiveness longer than both nonbenzodiazepine sleeping pills like zopiclone or standard benzodiazepines used for treating insomnia such as nitrazepam or oxazepam.

Skeletal Muscle Relaxation:

A single oral dose of one to two milligrams of etizolam is usually enough to reduce symptoms of stress-related muscle pain and induce a state of physical and mental well-being. Due to its anticonvulsant and skeletal muscle relaxant properties, etizolam can ease the physical pain caused by tense muscles, relaxing them, and reducing or killing the pain. Etizolam is especially useful for stress-related pain.

Recreational Use:

For those using etizolam as a recreational drug-taking, a three to five-milligram dose will cause a mellow, drowsy high with feelings of peace and calm. Doses higher than three milligrams a day are considered to be recreational. High doses of etizolam (5mg and up) can cause memory loss, confusion, impaired motor function, reduced inhibitions, slurred speech, drowsiness, and euphoria. The high from etizolam is similar to that of the Xanax (alprazolam) or liquor but more lucid, less tiring, and without the toxic effects and hangover associated with alcohol consumption.


At higher doses of three milligrams and above etizolam can cause euphoria, drowsiness, and a state of disinhibition comparable to the effects of alcohol. Unlike alcohol, however, etizolam doesn’t cause nausea or hangovers. The high from etizolam is similar to that of traditional benzodiazepines such as Xanax (alprazolam) or Ativan (lorazepam) but a little less sedating while still providing the same euphoria and relaxation. Experienced users should only take doses higher than five milligrams. Doses this high can cause powerful feelings of euphoria, significant loss of inhibition and motor function, retrograde amnesia, and difficulty staying awake.

  • Etizolam Tablets 1mg
  • Etizolam Tablets 2mg

Reverse Tolerance:

Etizolam has a unique trait in that users often develop a reverse tolerance to its effects, requiring smaller and smaller doses to achieve the same result. In comparison, other drugs and benzodiazepines cause people to develop a tolerance to their results, requiring higher doses over time. While this reverse tolerance phenomenon does eventually even out with repeated use, it makes etizolam highly desirable as a recreational substance. Compared to the classic benzodiazepines, etizolam is less likely to cause addiction, tolerance, or dependence. While it still delivers the same type of high as standard short-acting benzodiazepines.

Addiction, Dependence, and Withdrawal:

As with classic benzodiazepines, long-term use of etizolam can cause addiction and dependence. Abruptly stopping taking etizolam could result in a dangerous condition known as benzodiazepine withdrawal syndrome. Symptoms of benzodiazepine withdrawal include rebound insomnia and anxiety, sweating, hallucinations, and in rare cases seizures. It is important to note that according to several studies etizolam has been proven to be less likely to cause tolerance and dependence to develop than true benzodiazepines such as Valium (Diazepam) or Klonopin (clonazepam) making it less addictive than them as well. Etizolam has a relatively short half-life of just over six hours long, comparable to the short-acting benzodiazepines lorazepam and alprazolam.

Etizolam Overdose:

While the projected lethal dose of etizolam for a human being is much higher than the doses recommended above. It is still important to use caution when taking amounts more significant than three milligrams per day. When taking etizolam, it is advisable to avoid using another central nervous system (CNS) depressant such as alcohol, oxycodone, or alprazolam as these types of drugs can compound the effects of etizolam and cause potentially life-threatening respiratory depression. In severe emergency cases, an etizolam overdose can be reversed with the benzodiazepine overdose antidote, flumazenil.

Safety Profile:

Etizolam is one of the safest drugs to take due to its low dose threshold and high LD50. This means that while the beneficial effects of etizolam require only a few milligrams to attain it would take hundreds of times the maximum recommended dose to cause serious harm. To date, no overdose deaths have been linked to the consumption of etizolam alone. But it is believed to have a lower LD50 than Valium. There have been no overdose deaths linked exclusively to Valium either. However. Etizolam’s record of safety, lack of severe side effects, and potency even at low doses make it an excellent choice for those looking for a safe and effective medication for anxiety and insomnia or a powerful and euphoric but not particularly dangerous recreational high.

Signs of an Etizolam Overdose:

Symptoms of an overdose include slurred speech,

  • Confusion
  • Ataxia (lack of coordination)
  • Short term memory loss
  • Falls
  • Difficulty staying awake
  • Unconsciousness
  • Shallow and slowed breathing
  • Blue skin
  • Nausea
  • Vomiting
  • A slowed heart rate and other symptoms of central nervous system (CNS) depression.

It is essential to be cautious when mixing etizolam with alcohol or other central nervous system depressants. It includes alcohol, opioids, or other benzodiazepines as their compounded effects can lead to overdose.

Etizolam Dosage Chart:

Purpose Dosage in Milligrams
Anxiety 1-2mg per day.
Insomnia 2mg at bedtime.
Recreation 3mg and over.

Benzodiazepine Dose Comparison Chart:

Substance Equivalent Dose in Milligrams
Etizolam 1mg
Alprazolam (Xanax) 1mg
Lorazepam (Ativan) 1mg
Diazepam (Valium) 10mg

1 thought on “Etizolam Dosage and Risks Involved in Overdose”

  1. Thanks for the awesome guide about Etizolam dosage. I did take etizolam first time a year ago. However, I always prefer low doses of etizolam to abstain from getting addicted to it.

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