Etizolam and Clonazolam are both influential members of the benzodiazepine drug class. It is also known as a minor tranquilizer. They are often taken for their anxiolytic, hypnotic, and euphoric effects. Both drugs will treat anxiety, panic attacks, and insomnia, and they both produce a similar recreational high. However, the impact of Clonazolam and Etizolam can vary widely, and each one has its drawbacks and benefits. It is essential to choose which substance works best for your intentions, whether they are medical or recreational.

The subjective and objective effects of Etizolam and Clonazolam vary, so it is essential to understand the specific effects, side effects, and other significant differences between the two drugs. This article will give you a brief overview of the main differences between Clonazolam and Etizolam, their pros, cons, and ultimately, which of the two substances is the best choice to take.

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Clonazolam and Etizolam Explained

1. Clonazolam

Clonazolam, sometimes called Clonitrazolam, is a powerful short-acting minor tranquilizer known as a triazolobenzodiazepine and nitrobenzodiazepine that has never been officially marketed. It was first synthesized in 1971 and found to be very potent compared to other benzodiazepines. One study found Clonazolam to be two and a half times the potency of Alprazolam (Xanax.) Clonazolam faded away into relative obscurity until recently when it was rediscovered and marketed as a designer drug. It is important not to confuse Clonazolam and Clonazepam as Clonazolam is much more powerful than Clonazepam and dosage mix-ups have resulted in unintentional overdoses. Clonazolam typically comes in tablet form as well as on blotter paper or dissolved into a volumetric solution. The pure powder itself is rarely used due to its potency in the microgram range and the difficulty of working with such small doses. Since it was never marketed, there are no pharmaceutical Clonazolam medications so the appearance of pills and blotter papers can vary significantly. Due to its extreme strength, it is considerably more dangerous than other benzodiazepines, and it has been banned in several countries as a result.

Effects:

Clonazolam is active as a potent anxiolytic sedative-hypnotic and skeletal muscle relaxant at doses as low as 0.5 milligrams. It is a central nervous system (CNS) depressant meaning that it slows your breathing and heart rate. A mild dose of Clonazolam will cause a sense of relaxation, drowsiness, and peace. It takes between ten and thirty minutes for an oral dose of Clonazolam to take effect. It lasts between six and ten hours. A moderate dose of one milligram can cause euphoria, dizziness, impaired motor function, sleepiness, and amnesia. At higher doses Clonazolam has a similar effect to drinking a large quantity of alcohol, causing slurred speech, euphoria, severely impaired motor functions (ataxia), difficulty staying awake and total amnesia including blackouts lasting multiple days in severe cases.

Pros:

• Clonazolam is very powerful, making it ideal for experienced users with high benzodiazepine tolerances.
• Its strength makes it an excellent choice for recreational users seeking a powerful high.
• Only a single dose is required to experience the full effects of Clonazolam, whereas other benzodiazepines like Oxazepam often require multiple doses to achieve the same level of intoxication.
• Clonazolam is more sedating than Etizolam which makes it more useful and fast-acting for dealing with severe insomnia and agitation.
• Clonazolam is stronger than Etizolam, so you can spend less for the same effect.

Cons:

• Clonazolam has not gone through any official testing or clinical trials. There is little to no scientific information about Clonazolam’s long-term effects on humans.
• The Clonazolam manufacturing process is unregulated.
• Clonazolam has a higher potential to cause tolerance, dependence addiction, and abuse than Etizolam.
• The extreme potency of Clonazolam makes accidental overdoses more dangerous. It is believed to have a lower LD50 than Etizolam or other benzodiazepines.
• When used as a hypnotic for insomnia Clonazolam doesn’t allow for regular sleep structure. Clonazolam can lead to hangover effects the morning after use and daytime drowsiness.
• Clonazolam is often mistaken for the weaker prescription tranquilizer Clonazepam which could make unintentional overdoses more likely.
• Clonazolam has a lower lethal dose than Etizolam.
• Clonazolam will cause benzodiazepine withdrawal syndrome if taken for long periods. Clonazolam should not be stopped altogether at once but somewhat slowly tapered down in dosage.

2. Etizolam

Etizolam is not a true benzodiazepine but rather a derivative called a thienotriazolodiazepine. It was discovered in 1973 and approved for medical use in 1983. One milligram of Etizolam is equal in strength to a half milligram of Alprazolam, a half milligram of clonazepam, and ten milligrams of Valium. Although it was not as popular as the benzodiazepines prescribed in the West, Etizolam has been prescribed by doctors in countries such as India and Japan for decades. It takes between fifteen and thirty minutes to start feeling the effects after taking an oral dose of Etizolam. The effects peak about two to three hours after dosing and last between five and seven hours. Unlike Conazolam, Etizolam has undergone full clinical trials, and testing and its effects have been thoroughly investigated. Brand names include Etizola, Etizest, Etilaam, and Depas. It is available in many forms including pink pills, round green tablets, blotter papers, dissolved in a solution for volumetric dosing or only as a pure white powder. Etizolam pills are typically available in one and two-milligram strengths. Etizolam is believed to be less likely to cause intolerance, dependence, and addiction than classical benzodiazepines like Diazepam or especially Clonazolam. It is also known to be an effective muscle relaxant and anticonvulsant medication.

Effects:

Etizolam and Clonazolam share many of the same results. Both are powerful anxiolytic drugs, both can cause drowsiness and be used to treat insomnia, and both can deliver a euphoric high. But there are several key differences between the effects of Etizolam and Clonazolam. Etizolam has a rare reverse tolerance effect in which it becomes more rather than less potent as time goes on, although this fades with repeated use. Etizolam is less sedating than most benzodiazepines. It is equally effective as an anti-anxiety and panic attack drug, making it ideal for daytime use. Rare side effects include blepharospasm (an eye twitch) and in sporadic cases minor skin lesions. A single milligram causes the user to feel calm and relaxed but still leaves them able to focus. Two milligrams is the ideal dose to induce drowsiness before bed when treating insomnia. Taking three milligrams of Etizolam and higher produces a state of intoxication similar to alcohol with memory loss, blurred vision ataxia (loss of motor coordination) dizziness, euphoria, blackouts, and difficulty staying awake, although without nausea and hangover.

Pros:

• Etizolam underwent clinical trials and thorough testing by doctors and pharmaceutical experts before being released to the general public.
• Etizolam is equally useful for anxiety and insomnia without causing daytime drowsiness.
• Etizolam does not affect the body’s natural sleep structure whereas Clonazolam does, making it a longer-lasting and more effective sleep aid.
• It can be euphoric at reasonably low doses (three milligrams.)
• To date, there are no known overdoses from Etizolam alone.
• Etizolam has a rare reverse tolerance effect.
• Etizolam is less addictive than other benzodiazepines, including Clonazolam.
• The long-term side effects of Etizolam are well known and studied.

Cons:

• Etizolam is less powerful than Clonazolam, so more is needed to achieve the same effect.
• Etizolam causes less sedation than Clonazolam, making Clonazolam preferable for treating insomnia.
• Clonazolam lasts up to three hours longer than Etizolam does.
• Higher doses of Etizolam are required to achieve the same effect as a lower dose of Clonazolam.
• Etizolam has rare side effects like skin lesions and blepharospasms associated with long-time use.
• It can cause benzodiazepine withdrawal syndrome with long-term use.

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Etizolam Or Clonazolam?:

Clonazolam and Etizolam share many of the same traits. They are both sedative-hypnotics, both related to benzodiazepines, and have similar effects, albeit at different doses. However, Etizolam is the better option for several reasons. The most important one being that there isn’t much information about how Clonazolam affects the human body. Etizolam has been thoroughly tested and marketed to patients for decades and has an established record as a safe and useful medication. Clonazolam, on the other hand, is still very much an unknown substance to the medical community. Its lethal dose in humans and possible side effects are still not fully understood. Etizolam, on the other hand, is known to be relatively safe by itself, and there are established dose ranges for anxiety, insomnia, and recreation. Etizolam also becomes more powerful each time you take it while Clonazolam will feel less powerful each time as your tolerance increases. The effects of each drug are relatively similar in large doses, but it would require more Etizolam than Clonazolam to become intoxicated or to overdose on. Etizolam is safer, more reliable, and unlike Clonazolam, it doesn’t disrupt the natural sleep-wake cycle. Etizolam is more useful for the daytime treatment of panic attacks and anxiety without becoming too impairing or sedating while still providing an enjoyable recreational experience.